Multiple pathways are involved in the mechanism by which recurrence-associated miRNAs regulate malignancy progression, such as the tumor-associated pathways Wnt/β-catenin signaling pathway (hsa-miR-769-3p), ERK signaling (hsa-miR-193a-3p), and AKT-mTOR pathway (hsa-miR-193a-5p) [16, 18, 19]. This evidence concerns the gene AKT1 and neoplasm.