To determine if DEAR1 plays a role in the regulation of stem/progenitor activity, we examined DEAR1 E6-CshR and E6-DshR HMEC clones for expression of aldehyde dehydrogenase (ALDH1A1), an established marker of stem/progenitor cells that is overexpressed in both normal and cancer stem cells31. This evidence concerns the gene TRIM62 and cancer.