To note, PK5L1940 pancreatic cancer cells are characterized by Kras mutation, while BRAF (BRAFV600EΔTRZI) colorectal cancer cells characterized by Braf mutation were obtained from organoids and subcutaneous inoculation of these cells in animals that led to the development of serrated colon tumors [15, 16]. The gene discussed is BRAF; the disease is colonic neoplasm.