While we did not find a significant increase in IL-4 (Fig. 5a), which is a type II immune response cytokine, but also known to be pro-tumorigenic cytokine, we found that the type II immune cytokine IL-5 was significantly increased in mice with gastrointestinal tumors treated with Th2 cells (Fig. 5b). Here, IL5 is linked to digestive system neoplasm.