In contrast, PMA or TNF-α treatment at 9 dpi failed to induce GFP expression above background in WT CEM-SS cells treated at 0 dpi with TAK-981, or in the ΔSMC5 CEM-SS clone either in the absence or presence of TAK-981 treatment at 0 dpi (Fig. 4a,b), even though the initial infection of these cells, as measured by GFP expression, was actually higher than seen in WT CEM-SS cells (Extended Data Fig. 6a). Here, TNF is linked to infection.