Cell proliferation and migration processes were also assessed in these conditions, exhibiting a synergistic inhibition effect on cell viability (Fig. 5c), colony formation ability (Fig. 5d) and Ki67 proliferation index (Fig. 5e, Supplementary Fig. S5b) when HCC cells were treated with lenvatinib after NRP1 silencing. The gene discussed is MKI67; the disease is hepatocellular carcinoma.