We confirmed increased expression of PURPL in HCC using data from The Cancer Genome Atlas (TCGA) and Genetype-Tissue Expression (GTEx) database (P = 4.10E-8, TCGA-Liver Hepatocellular Carcinoma (LIHC): n = 369, Normal liver tissue: n = 160) (Fig. 1d). Here, PURPL is linked to hepatocellular carcinoma.