The most common NSCLC-associated EGFR mutations are the point mutation replacing leucine with arginine in exon 21 (L858R) and in-frame deletions in exon 19 (19del), which account for ~85% of all EGFR mutations and are associated generally with having adenocarcinoma histology5,6. Here, EGFR is linked to non-small cell lung carcinoma.