For example, as shown in Fig. 4b, a total of 98.7% of EGFR(+)HX103(+) cells were detected in a tumor tissue (#12-T) from a patient with EGFR L858R (identified by Sanger sequencing, Supplementary Fig. 29), and the percentage values of EGFR(+) and HX103(+) cells were 98.9 and 99.6%, respectively (Supplementary Fig. 26). This evidence concerns the gene EGFR and neoplasm.