SCN5A and Prolonged QT interval: For example, recent GWAS of thoracic aorta diameters among healthy individuals implicate known Mendelian aortopathy genes like FBN170,71, GWAS of electrocardiographic traits find long-QT syndrome-associated genes like SCN5A are associated with variation in many other subclinical electrocardiographic traits72, and GWAS of both left- and right-heart structure/function among healthy individuals identify Mendelian cardiomyopathy genes23,73,74.