CRP-based triage demonstrated clinical utility in similar settings if it is necessary or desirable to prioritize use of confirmatory testing so that those tested have at least a 5% risk of pulmonary TB (i.e. a number willing to test of fewer than 20 confirmatory tests per true TB case detected), whilst confirmatory testing for all individuals who met our symptom-based enrolment criteria appears best below this threshold probability. The gene discussed is CRP; the disease is tuberculosis.