SF3B2 and breast cancer: Interestingly, the expression of 34 out of the 43 proximal interactors linked to the spliceosome correlated with a significant impact on the overall survival of BC patients (Fig 5A, S14 Table), including SNRNP40 (cluster 1), SF3B2 (cluster 2), SF3B5 (cluster 3), and SNW1 (cluster 4).