We performed a similar analysis with members of the positive regulation of RNA metabolic process, which delineated 31 (out of 43) potential prognostic factors in the cohort of BC patients analyzed by RNA-seq (S5A Fig, S14 Table), including CNOT1 (cluster 1), ELF2 (cluster 2), and PAXBP1 (cluster 3). This evidence concerns the gene CNOT1 and breast cancer.