The results of the multivariate logistic regression analysis suggested that age (OR 1.036, 95% CI 1.003–1.069, p = 0.034), hypertension (OR 2.393, 95% CI 1.447–3.959, p = 0.001), and hyperuricemia (OR 2.036, 95% CI 1.147–3.616, p = 0.015) were independently associated with CKD after adjustment for overweight/obesity, waist circumference, BFP, hypertriglyceridemia, HDL-C, CRP, the FIB-4 score, the NFS, and remnant cholesterol (Table 4). The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.