In particular, xenografts derived from cell lines that showed a good response (response rating < 0.3) to elimusertib, such as GRANTA‐519 (MCL) and Lovo (CRC), also showed strong nuclear geminin, pATR, and pCHK1 signals, whereas those that showed a moderate response (response rating 0.3–0.6) to elimusertib, such as HCT116 (CRC) and KLN205 (murine lung cancer), showed moderate signals (Figure 3A). This evidence concerns the gene GMNN and colorectal carcinoma.