USP29 and colorectal carcinoma: Next, KIAA1429 was upregulated in SW620 cells via the transfection of pcDNA3.1-KIAA1429 (KIAA1429), followed by combination treatment with si-USP29#1 (p < 0.01, Figure 4A and 4B), to validate the role of KIAA1429 in malignant proliferation of CRC cells.