Compared with the si-USP29#1 + NC group, KIAA1429 upregulation enhanced SW620 cell proliferation (p < 0.01, Figure 4C– 4E), which indicated that KIAA1429 upregulation attenuated the inhibitory role of silencing USP29 in malignant proliferation of CRC cells. The gene discussed is USP29; the disease is colorectal carcinoma.