In PTEN‐knockout compared to wild‐type mice, the areal density of cortical SST‐IR interneurons is reduced (Vogt, Cho, Lee, Sohal, & Rubenstein, 2015), sociability and motor learning is impaired, and anxiety‐like behaviors are increased (Shin, Santi, & Huang, 2021). This evidence concerns the gene PTEN and Anxiety.