Firstly, the DNA‐PK and pDNA‐PK levels in MDSCs of tumor‐bearing mice PBMCs were detected by flow cytometry and analysis revealed that DNA‐PK levels in MDSCs, PMN‐MDSCs, and Mo‐MDSCs in tumor‐bearing mice PBMCs were significantly lower than those in healthy mice (Figure S7A,C,E). The gene discussed is PRKDC; the disease is neoplasm.