In contrast to NU7441's role in inhibiting DNA‐PK phosphorylation in 4 T1 cells, we found that NU7441 administration significantly increased the protein levels of DNA‐PK and pDNA‐PK in MDSC, PMN‐MDSCs, and Mo‐MDSCs in PBMCs of tumor‐bearing mice in vivo (Figure 5A–F). The gene discussed is PRKDC; the disease is neoplasm.