Of note, the compound showed also anti-proliferative activity against three NSCLC cell lines exhibiting different EGFR status, the observed IC50 values being 14.5 ± 0.3 μM (wt EGFR H1299 cell line), 19 ± 2 μM (mutant EGFR H1650 cell line), and 24 ± 2 μM (double mutant H1975 cell line).14 This evidence concerns the gene EGFR and non-small cell lung carcinoma.