PRF1 and neoplasm: scRNA-Seq analysis of Lin- CD127+ CD56- helper ILCs and Lin- CD127- CD56+ NK cells from the tumor and paired non-tumor tissue revealed four different g1 ILC clusters (collectively referred to as ILC1 by the authors), all of which expressed EOMES and other typical NK genes, including GZMB, PRF1, and CCL5[73].