FcγRIIIa expression differed between the three groups (Kruskal–Wallis H test; p = 0.01) and was reduced in early (Mann–Whitney test; p < 0.001), but not established RA (Mann–Whitney test; p = 0.22), when compared to HC (Fig. 4a). This evidence concerns the gene FCGR3A and rheumatoid arthritis.