TET2 and acute myeloid leukemia: Additionally, C-KIT, TET1, and TET2 could be used as potential useful markers for the diagnosis of AML especially when combined together as c-KIT + TET1 + TET2 achieved a sensitivity of 77.5%, and specificity of 100%, while c-KIT + TET1 achieved a sensitivity of 78.6%, and a specificity of 100%.