More importantly, the transplantation of ST2-deficient thymus, but not ST2-sufficient thymus, significantly promoted T cell-mediated egg granuloma formation to protect host tissues from egg-derived toxins in recipient mice infected with schistosome (Fig. 4m, n)29, as well as lengthened the survival of recipient mice with sepsis (Fig. 4o). The gene discussed is IL1RL1; the disease is Sepsis.