In a recent study where molecular testing was performed in 85 thyroid FNA specimens that were Bethesda IV-suspicious for a Hürthle cell neoplasm, EIF1AX mutations were found in 5 cases and, of those, three had surgical follow-up, two of which were HCC (including one with a co-TERT mutation) and one showed multinodular goiter on histologic evaluation [15]. The gene discussed is EIF1AX; the disease is multinodular goiter.