On the other hand, urinary NGAL had the highest diagnostic accuracy (DOR 17.9, 95% CI 12.3–26.3), which was significantly better than IL-18 (relative DOR 0.31, 95% CI 0.21–0.47), IL-18/Cr (relative DOR 0.56, 95% CI 0.34–0.94), KIM-1 (relative DOR 0.57, 95% CI 0.40–0.82), L-FABP (relative DOR 0.46, 95% CI 0.30–0.71), and TIMP-2 × IGFBP-7: 0.3 (relative DOR 0.28, 95% CI 0.10–0.79) for the occurrence of AKI in the setting of medical/mixed patients (upper panel in Table 5). Here, LCN2 is linked to acute kidney injury.