A total score of ≥ 2 points (the highest sensitivity option) or met criteria at least one of the following: age > 60 years old or pretreatment blood glucose ≤ 100 mg/dL (≤ 5.6 mmol/L) indicated a high risk for posttreatment levels 2 and 3 hypoglycemia in hyperkalemic patients treated with IV insulin and glucose. The gene discussed is INS; the disease is Hypoglycemia.