In this regard, genetic causes could have a significant role considering the recent observation that genetic risk alleles for ALS also include spinocerebellar ataxia-associated genes (i.e., ATXN1, ATXN2) (Tazelaar et al., 2020; van Rheenen et al., 2021). The gene discussed is ATXN2; the disease is amyotrophic lateral sclerosis.