The case of structural variants is especially interesting since several of the CNV loci identified in this study overlap with genomic regions previously implicated with developmental syndromes like autism spectrum disorder (2p16.3 [NRXN1 gene, Neurexin-1 protein]) (Tromp et al. 2021) or 22q11.2 deletion syndrome (Francisco 2022). This evidence concerns the gene NRXN1 and 22q11.2 deletion syndrome.