EGFR and non-small cell lung carcinoma: EGFR mutations represent one of the most common pathogenic genomic alteration in NSCLC patients, however, in the Latin American setting it has a heterogeneous frequency, for example, countries such Peru, Mexico, and Costa Rica have a high frequency of EGFR, similar to Asian populations, and countries such Argentina, Chile, and Uruguay have a frequency similar to North American and European population.10, 18