Common annotations among the 20 most significant pathways in leukemia cells included regulation of intrinsic and extrinsic apoptotic pathways, regulation of other types of cell death such as anoikis, necrosis or necroptosis, NFκB activity mediation, regulation of endopeptidase activity, and protein poly‐ubiquitination. The gene discussed is NFKB1; the disease is leukemia.