despite being assigned strong weights by the LASSO, and belong to a wide variety of cancer-associated pathways such as the Hippo pathway (e.g. YAP, TAZ) and inflammatory immune response (e.g. PDL1, NFKBP65_pS536) (Supplementary Fig. S7), consistent with the widespread dysregulation that is typical of cancer40. The gene discussed is CD274; the disease is cancer.