We performed WB detection of GPX4 protein in 5 paired gastric cancer tissues and adjacent normal gastric mucosa tissue samples, the results showed that GPX4 protein levels were higher in gastric cancer tumor tissues than in adjacent normal gastric mucosa tissues (Fig. S8A), which is in good agreement with the expression of CST1 in Fig. 1L. The gene discussed is CST1; the disease is gastric cancer.