CXCL5 and Familial prostate cancer: We further confirmed that Cxcl5 was downregulated, and Cxcl9/10 were upregulated in the FACS-isolated stromal cells from both RM-1 xenografts (Fig. 4d) and prostate cancer tissues of Col1a2-Foxf2-TRAMP mice (Fig. 4e) as compared to their respective controls.