H&E staining shows that the control (Col1a2-TRAMP) mouse prostates uniformly and diffusely displayed invasive adenocarcinomas in the dorsal and anterior lobes, whereas Col1a2-Foxf2-TRAMP mouse prostates showed a spectrum of less advanced lesions in the same lobes (Fig. 3c). The gene discussed is COL1A2; the disease is adenocarcinoma.