GO enrichment analysis showed that these DEGs were mainly enriched in immunoglobulin production, immunoglobulin-mediated immune response, immunoglobulin-mediated immune response, immunoglobulin complex, and antigen binding; KEGG pathway analysis showed that these DEGs were mainly enriched in amoebiasis, haematopoietic cell lineage, and IL-17 signalling pathway (Fig. 6a, b). Here, IL17A is linked to amebiasis.