A recent study reported an establishment of a predictive model generated by machine learning that included pretreatment cytokine levels (IL-8 and CCL2), clinical factor (hypertension), and radiation dosimetric factor (mean lung dose) for radiation pneumonitis grade higher or equal to 2 in patients with non-small lung cancer receiving radiotherapy [62]. The gene discussed is CXCL8; the disease is hypertensive disorder.