INS and type 2 diabetes mellitus: With the performance of the web tool GEO2R, both the differentially expressed genes (DEGs) in skeletal muscle between T2DM subjects and the normoglycemic insulin-resistant subjects with parental family history (PFH) of T2DM subjects, and the DEGs between T2DM subjects and the normoglycemic insulin resistant subjects without PFH of T2DM subjects were identified.