With double immunofluorescence labeling for claudin‐11/OSP and MBP, NFASC and MBP, and Caspr1 and MOG, claudin‐11/OSP, NFASC, and Caspr1 showed a similar paranodal staining pattern between MSA Stage I and controls (Figure 3M, Aj). The gene discussed is CLDN11; the disease is multiple system atrophy.