We did not observe an association between high CD8 TILs and prognosis as previously described in the larger cohort of 343 cases that was scored with a 4-point ordinal scoring system [2], but we showed lower densities of CD8+ T cells in the tumor epithelium compared to stroma implying little CD8+ T cell/tumor antigen interaction in MOC. This evidence concerns the gene CD8A and neoplasm.