In a small cohort study (n = 7), Kesler et al. showed superiority of 68Ga-PSMA PET over 18F-FDG PET-CT in imaging newly diagnosed HCC [25]; all tumors, except for one lesion showed abnormal 68Ga-PSMA uptake higher than that of the surrounding liver parenchyma, with a mean uptake 3.6 times higher than the normal surrounding liver background. This evidence concerns the gene FOLH1 and hepatocellular carcinoma.