Although ASCT1 protein expression was reported in the isolated human brain microvessels [55], capillary endothelial cells of embryonic and neonatal mouse brains [52], and rodent astrocytes and neurons [51, 56, 57], alterations in ASCT1 expression and function in the NVU cells in AD patients have not been investigated. The gene discussed is SLC1A4; the disease is Alzheimer disease.