The comparison of changes in protein expression of transporters in the isolated brain microvessels between 5xFAD mice and TgF344-AD rats versus corresponding WT control animals demonstrated TgF344-AD-rat-specific upregulation of Abcg2, Abcc1, and FATP1 expression and 5xFAD-mouse-specific upregulation of ASCT1 and 4F2hc as well as LAT1 downregulation (Table 1). The gene discussed is SLC1A4; the disease is Alzheimer disease.