The comparison of absolute protein expression levels of four ABC and two SLC transporters in the brain cortical tissue of 8-month-old 5xFAD to another transgenic AD model, 16–17-month-old APdE9 mice, revealed only twice higher protein expression of Abcb1 in APdE9 mice compared to 5xFAD mice (Fig. 2e). This evidence concerns the gene ABCB6 and Alzheimer disease.