Similar to the expression in brain microvessels, the absolute protein expression of some transporters such as Abcg2, Abcc1, Abca1, ASCT1, GLUT1, LAT1, and 4F2hc was more than twice higher in 5xFAD mice compared to TgF344-AD rat model (Fig. 3c). Here, ABCG2 is linked to Alzheimer disease.