Multiple MMP family members, such as collagenase 1 (MMP-1), gelatinase A (MMP-2), gelatinase B (MMP-9), matrilysin (MMP-7), and membrane-type (MT)-MMPs, have been correlated with tumor progression such as the formation of metastasis and bad prognosis [43,44]. This evidence concerns the gene MMP9 and neoplasm.