Longitudinal analyses of these markers indicate different degrees of inflammation (increased levels of IL-6 and CRP), infection (increased levels of ferritin and neutrophils and decreased levels of lymphocytes), thrombosis (increased D-dimer and thrombin associated with decreased fibrinolysis), and tissue damage (increased LDH, AST, and ALT, and decreased fibrinogen) [30]. Here, CRP is linked to infection.