IFITM3 and infection: It has been demonstrated that IFITM3 restricts the infection of a variety of viruses in vitro, such as influenza A virus (IAV), Ebola virus (EBOV), Marburg virus (MAVR), SARS coronavirus (SARS–CoV) [1,2], human immunodeficiency virus (HIV–1) [3], Dengue virus (DENV) [4] and Zika virus (ZIKV) [5].