Capable of interacting with tumor necrosis factor (TNF) receptor-related factor 6 (TRAF6), upregulating the tryptophan-aspartate repeat domain (WDR)5 expression, or suppressing Phosphoinositide 3-kinases (PI3Ks) and protein kinase B (AKT) signaling pathways, TXNIP can inhibit lung cancer cell multiplication and migration [67]. Here, TRAF6 is linked to lung carcinoma.