RHEB and glioblastoma: Incubation of glioblastoma cell lines with AMC11 (1 μM)–siRNA (100 nM) CDplexes caused a significant decrease (ranging from 75 to 90%) in both p42-MAPK (Figure S7) and Rheb (Figure S8) protein levels in C6 rat, GL261 mouse, and human U87 glioblastoma cell lines.