TNF and cancer: The inflammatory/hypoxic environment of tumors and the secretion of various cytokines, such as TNF-α, IL-8, CXCL1, and granulocyte-CSF (G-CSF), recruit neutrophils and induce NETosis in tumors, thereby participating in multiple stages of cancer progression and promoting the malignant transformation of diseases (Figure 6) [185,186,187].