DMD and Duchenne muscular dystrophy: Another study assessed the efficacy of 11 different DMD-antisense U7 snRNAs using lentivirus and AAV in in vitro and in vivo settings, respectively [117], and reported that different U7 snRNA constructs could be combined into a single AAV vector to achieve skipping of multiple exons and potentially restore functional DMD protein for Duchenne muscular dystrophy (DMD).