SHOX and Prader-Willi syndrome: RhGH treatment has been approved in Europe and the USA for several different conditions associated with short stature, including Growth Hormone Deficiency (GHD), Small for Gestational Age (SGA), Turner Syndrome (TS), Prader-Willi Syndrome (PWS), Russell Silver Syndrome (RSS), Short stature HomeobOX-containing gene (SHOX) deficiency, Idiopathic short stature (ISS), Chronic Renal Insufficiency (CRI), and Noonan Syndrome (NS) [1,3,5,6,7,8].