Nowadays, lung colonization by the sessile form of this bacterium holds a challenging threat, mostly in patients affected by cystic fibrosis (CF) [15,16], a genetic disease caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, which controls chloride and bicarbonate transport mainly at the apical membrane of secretory epithelia, including those at the airways [17,18]. Here, CFTR is linked to cystic fibrosis.