The participants with new-onset hyperuricemia were older, had increased rates of hypertension and DM, elevated SBP, DBP, BMI, fasting glucose, total cholesterol, hemoglobin, triglyceride, uric acid, GGT, albumin, ALT and AST, and a lower eGFR and total bilirubin than those without new-onset hyperuricemia. The gene discussed is ALB; the disease is Hypertension.