INS and Insulin resistance: Previous results from our group showed that increased populations of Prevotella associated with the intake of d-fagomine did not have any significant effect on the fasting blood levels of either glucose or insulin in healthy rats [9]; indeed, such populations even appeared together with a reduction in the elevation of the Homeostatic Assessment Model for Insulin Resistance (HOMA-IR) driven by a high-fat diet in rats [29].