Compared to the control group, the levels of proinflammatory cytokines (IL-1β and IL-6) in serum were markedly higher (p = 0.019, p = 0.0362), and the level of anti-inflammatory cytokine (IL-10) in serum was lower in DM model group (p = 0.0013). The gene discussed is IL1B; the disease is diabetes mellitus.