A study by Bale et al., 2017, from India which comparing two distinct Indian ethnicities and showed that in South Indian ethnics, higher susceptibility to NAFLD was associated with the TM6SF2 rs58542926 variant (OR = 2.7), while for North-East Indian ethnicities, an rs2281135 variant of PNPLA3 gene was associated with higher susceptibility to NAFLD (OR = 2) [124]. The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.