The study by Mansoor et al., 2021, on a cohort of obese Hispanic children in the U.S. showed that, while NAFLD was significantly increased with PNPLA3 rs738409 C > G polymorphism ((OR = 3.7 (1.5–9.4)), the odds of NAFLD in the presence of the MBOAT7 rs641738 variant was lower (OR = 0.19 (0.04–0.83)) [113]. The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.